The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 30, 2020
Filed:
Oct. 14, 2016
Applicants:
Celgene Corporation, Summit, NJ (US);
Agios Pharmaceuticals, Inc., Cambridge, MA (US);
Inventors:
Vivek Saroj Kumar Chopra, South San Francisco, CA (US);
Jorge DiMartino, Belmont, CA (US);
Laurie A. Kenvin, New Hope, PA (US);
Robert Douglas Knight, Berkeley Heights, NJ (US);
Kyle MacBeth, San Francisco, CA (US);
Krishnan Viswanadhan, East Hanover, NJ (US);
Qiang Xu, Basking Ridge, NJ (US);
Samuel V. Agresta, Lexington, MA (US);
Assignees:
Celgene Corporation, Summit, NJ (US);
Agios Pharmaceuticals, Inc., Cambridge, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/53 (2006.01); A61K 31/7068 (2006.01); A61P 35/02 (2006.01); A61K 31/706 (2006.01);
U.S. Cl.
CPC ...
A61K 31/53 (2013.01); A61K 31/7068 (2013.01); A61P 35/02 (2018.01); A61K 31/706 (2013.01); A61K 2300/00 (2013.01);
Abstract
Provided are methods and compositions for treating cancers in patients carrying an IDH2 mutation using a combination of an inhibitor of a mutant IDH2 enzyme and a DNA demethylating agent.