The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 30, 2020
Filed:
Aug. 15, 2016
University of Florida Research Foundation, Inc., Gainesville, FL (US);
Kyle Douglas Allen, Gainesville, FL (US);
Jon Paul Dobson, Gainesville, FL (US);
Elena Georgina Yarmola, Gainesville, FL (US);
Zachary Kaufman, Plantation, FL (US);
David P. Arnold, Gainesville, FL (US);
UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC., Gainesville, FL (US);
Abstract
Provided herein is a magnetic apparatus for collecting superparamagnetic particles from a subject. The superparamagnetic particles are previously injected into the subject and have ligands bound thereto that are specific for one or more non-cell biomarkers. In one embodiment, the superparamagnetic particles are injected into and retrieved from a cavity such as a joint cavity. These compositions and methods allow for the sequestration and removal of inflammatory mediators, as both a diagnostic of the local immune response and a therapeutic that can reduce inflammation in the local disease environment.