The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 30, 2020
Filed:
Mar. 27, 2015
University of Washington, Seattle, WA (US);
Koninklijke Philips N.v., Eindhoven, NL;
Ari Partanen, Andover, MA (US);
Vera Khokhlova, Seattle, WA (US);
Navid Farr, Seattle, WA (US);
Donghoon Lee, Seattle, WA (US);
Wayne Kreider, Seattle, WA (US);
Tatiana Khokhlova, Seattle, WA (US);
Adam Maxwell, Seattle, WA (US);
Yak-Nam Wang, Seattle, WA (US);
George Schade, Seattle, WA (US);
Michael Bailey, Seattle, WA (US);
UNIVERSITY OF WASHINGTON, Seattle, WA (US);
KONINKLIJKE PHILIPS N.V., Eindhoven, NL;
Abstract
Example embodiments of system and method for magnetic resonance imaging (MRI) techniques for planning, real-time monitoring, control, and post-treatment assessment of high intensity focused ultrasound (HIFU) mechanical fractionation of biological material are disclosed. An adapted form of HIFU, referred to as 'boiling histotripsy' (BH), can be used to cause mechanical fractionation of biological material. In contrast to conventional HIFU, which cause pure thermal ablation, BH can generate therapeutic destruction of biological tissue with a degree of control and precision that allows the process to be accurately measured and monitored in real-time as well as the outcome of the treatment can be evaluated using a variety of MRI techniques. Real-time monitoring also allow for real-time control of BH.