The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 23, 2020

Filed:

Sep. 13, 2017
Applicant:

Lipogems International S.p.a., Milan, IT;

Inventors:

Carlo Tremolada, Milan, IT;

Carlo Ventura, Bologna, IT;

Milford Graves, Jamaica, NY (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/0775 (2010.01); C12M 1/42 (2006.01); A61H 23/00 (2006.01); C12N 13/00 (2006.01); A61B 17/00 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0667 (2013.01); A61H 23/00 (2013.01); C12M 35/04 (2013.01); C12N 13/00 (2013.01); A61B 2017/00969 (2013.01); C12N 2527/00 (2013.01);
Abstract

The invention relates to a process for preparing a non-expanded tissue derivative, that is not subjected to cell proliferation in vitro, comprising a vascular-stromal fraction enriched in stem and multipotent elements, such as pericytes and/or mesenchymal stem cells, or for preparing non-embryonic stem cells obtained from a tissue sample or from said derivative, wherein said tissue derivatives or said cells are subjected to vibrations derived from a heart sound such to control the degree of differentiation or possible differentiation of said stem and multipotent elements into several other types of cells that is to optimize their potency. The invention relates also to a device for carrying out said process, to stem cells obtainable by the process as well as a drug for the regeneration of an animal tissue.


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