The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 23, 2020
Filed:
Jun. 27, 2017
Applicant:
Flodesign Sonics, Inc., Wilbraham, MA (US);
Inventors:
Thomas J. Kennedy, III, Wilbraham, MA (US);
Bart Lipkens, Hampden, MA (US);
Stanley J. Kowalski, III, Wilbraham, MA (US);
Anthony E. English, Longmeadow, MA (US);
Assignee:
FloDesign Sonics, Inc., Wilbraham, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 13/00 (2006.01); B01D 17/06 (2006.01); C12M 1/42 (2006.01); C12M 1/00 (2006.01); B01D 21/28 (2006.01); B06B 1/06 (2006.01); B01D 17/04 (2006.01); C07K 1/14 (2006.01); G10K 9/122 (2006.01); H01L 41/053 (2006.01); H01L 41/09 (2006.01);
U.S. Cl.
CPC ...
C12M 35/04 (2013.01); B01D 17/04 (2013.01); B01D 17/06 (2013.01); B01D 21/283 (2013.01); B06B 1/0622 (2013.01); C07K 1/145 (2013.01); C12M 23/14 (2013.01); C12M 29/04 (2013.01); C12M 35/02 (2013.01); C12M 47/02 (2013.01); C12M 47/10 (2013.01); C12N 13/00 (2013.01); G10K 9/122 (2013.01); H01L 41/053 (2013.01); H01L 41/096 (2013.01);
Abstract
A series of multi-dimensional acoustic standing waves is set up inside a growth volume of a bioreactor. The acoustic standing waves are used to hold a cell culture in place as a nutrient fluid stream flows through the cell culture. The nutrient fluid stream dislodges some cells from the cell culture, which can then be recovered for cell therapy applications. The cell culture continues to expand and reproduce, permitting continuous recovery of cells from the bioreactor.