The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 23, 2020
Filed:
Dec. 10, 2015
The General Hospital Corporation, Boston, MA (US);
Novartis Ag, Basel, CH;
Qing Sheng, Sharon, MA (US);
Rakesh K. Jain, Freemont, CA (US);
Vasileios Askoxylakis, Cambridge, MA (US);
Gino B. Ferraro, Somerville, MA (US);
Dai Fukumura, Newton, MA (US);
David P. Kodack, Boston, MA (US);
Novartis AG, Basel, CH;
The General Hospital Corporation, Boston, MA (US);
Abstract
The present invention relates to a pharmaceutical combination which comprises (a) a phosphatidylinositol 3-kinase inhibitor or pharmaceutically acceptable salt thereof, and (b) a Her3 antagonist, for simultaneous, separate or sequential administration for the treatment of breast cancer brain metastases; a method of treating a subject having a breast cancer brain metastases comprising administration of said combination to a subject in need thereof; use of such combination for the treatment of breast cancer brain metastases; and a commercial package comprising such combination.