The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 23, 2020
Filed:
Dec. 08, 2014
Applicant:
Novimmune S.a., Geneva, CH;
Inventors:
Emmanuel Monnet, Geneva, CH;
Limin Shang, Geneva, CH;
Susana Salgado-Pires, Geneva, CH;
Walter Ferlin, Saint Cergues, FR;
Greg Elson, Collonges sous Saleve, FR;
Assignee:
NovImmune SA, Geneva, CH;
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); A61K 39/00 (2006.01); C07K 16/28 (2006.01); A61K 35/28 (2015.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07K 16/28 (2013.01); A61K 35/28 (2013.01); A61K 39/3955 (2013.01); A61K 45/06 (2013.01); C07K 16/2896 (2013.01); A61K 2039/505 (2013.01); C07K 2317/30 (2013.01); C07K 2317/33 (2013.01); C07K 2317/34 (2013.01); C07K 2317/76 (2013.01);
Abstract
This invention relates generally to anti-Toll-like Receptor 4 (TLR4 antagonists) including antibodies that specifically bind Toll-like Receptor 4 (TLR-4), to methods of using the anti-TLR4 antagonists as therapeutics and to methods of using the anti-TLR4 antagonists for inhibiting, delaying the progression of, or otherwise ameliorating a symptom of Graft-versus-Host disease (GvHD) and/or improving survival of GvHD subjects and/or transplanted biological materials in subjects.