The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 23, 2020

Filed:

Oct. 09, 2016
Applicants:

Xiamen University, Xiamen, CN;

Yang Sheng Tang Company, Ltd., Haikou, CN;

Inventors:

Wenxin Luo, Xiamen, CN;

Bing Zhou, Xiamen, CN;

Juan Zhang, Xiamen, CN;

Quan Yuan, Xiamen, CN;

Tianying Zhang, Xiamen, CN;

Jun Zhang, Xiamen, CN;

Ningshao Xia, Xiamen, CN;

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/08 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/082 (2013.01); A61K 2039/505 (2013.01); C07K 2317/24 (2013.01); C07K 2317/56 (2013.01); C07K 2317/565 (2013.01); C07K 2317/622 (2013.01); C07K 2317/92 (2013.01); C07K 2317/94 (2013.01);
Abstract

The invention provides an antibody (in particular, a humanized antibody) against hepatitis B surface antigen (HBsAg), a nucleic acid molecule encoding the same, a method for preparing the same, and a pharmaceutical composition comprising the same. The invention also provides use of the antibody and pharmaceutical composition. The antibody and pharmaceutical composition according to the invention can be used for preventing and/or treating HBV infection or a disease associated with HBV infection (such as Hepatitis B), for neutralizing HBV virulence in a subject (such as human), or for reducing the serum level of HBV DNA and/or HBsAg in a subject.


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