The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 23, 2020

Filed:

Sep. 08, 2016
Applicant:

Jubilant Biosys Limited, Karnataka, IN;

Inventors:

Saravanan Vadivelu, Bangalore, IN;

Sridharan Rajagopal, Bangalore, IN;

Manjunatha M. Ramaiah, Bangalore, IN;

Pavan Kumar Gondrala, Bangalore, IN;

Murugan Chinnapattu, Bangalore, IN;

Dhanalakshmi Sivanandhan, Bangalore, IN;

Payal Kiran Parikh, Bangalore, IN;

Chandrika Mulakala, Bangalore, IN;

Assignee:

JUBILANT BIOSYS LIMITED, Karnataka, IN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4353 (2006.01); A61P 35/00 (2006.01); C07D 471/04 (2006.01); C07D 471/14 (2006.01); C07D 491/044 (2006.01); C07D 491/14 (2006.01); C07D 495/14 (2006.01); C07D 513/14 (2006.01); C07D 493/14 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07D 495/14 (2013.01); A61P 35/00 (2018.01); C07D 471/14 (2013.01); C07D 491/14 (2013.01); C07D 493/14 (2013.01); C07D 513/14 (2013.01); A61K 45/06 (2013.01); A61K 2300/00 (2013.01);
Abstract

The present disclosure describes heterocyclic compounds of Formula I or, its stereoisomers, pharmaceutically acceptable salts, complexes, hydrates, solvates, tautomers, polymorphs, racemic mixtures, optically active forms and pharmaceutically active derivatives thereof and pharmaceutical compositions containing them as the active ingredient. The present disclosure also describes the synthesis and characterization of aforementioned compounds to exhibit high anticancer activity. The compounds of the present disclosure are useful as medicaments and their use in the manufacture of medicaments for treatment, prevention, or suppression of diseases, and conditions mediated by one or more BET family of bromodomains.


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