The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 23, 2020
Filed:
Jul. 11, 2017
Netherlands Translational Research Center B.v., Oss, NL;
Adrianus Petrus Antonius De Man, Hurwenen, NL;
Joost Cornelis Marinus Uitdehaag, Oss, NL;
Jan Gerard Sterrenburg, Renkum, NL;
Joeri Johannes Petrus De Wit, Boekel, NL;
Nicole Wilhelmina Cornelia Seegers, Heesch, NL;
Antonius Maria Van Doornmalen, Kerkdriel, NL;
Rogier Christian Buijsman, Berghem, NL;
Guido Jenny Rudolf Zaman, Berghem, NL;
Abstract
The invention relates to a compound of Formula I: Formula I, or pharmaceutically acceptable enantiomers, or salts thereof. The present invention also relates to the use of compounds of Formula (I) as selective inhibitors of tryptophan 2,3-dioxygenase. The invention also relates to the use of the compounds of Formula (I) for the treatment or prevention of cancer and central nervous system disease or disorder, either as a single agent or in combination with other therapies.