The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 23, 2020

Filed:

Mar. 28, 2018
Applicant:

Quimica Sintetica, S.a., Barcelona, ES;

Inventors:

Giuseppe Barreca, Montevecchia, IT;

Giovanni Marras, Galliate, IT;

Fabio Morana, Novara, IT;

Assignee:

Quimica Sintetica, S.A., Barcelona, ES;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 315/00 (2006.01); C07C 317/00 (2006.01); C07C 261/00 (2006.01); C07C 315/04 (2006.01); C07C 251/16 (2006.01); C07C 317/28 (2006.01);
U.S. Cl.
CPC ...
C07C 315/04 (2013.01); C07C 251/16 (2013.01); C07C 317/28 (2013.01);
Abstract

It is described an industrially viable and advantageous process for the preparation of racemic beta-aminosulfone (1), an useful intermediate for the preparation of N-(2-((1S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl)acetamide, also known as Apremilast, the latter being suitable for use in methods of treating, preventing and/or managing psoriasis or psoriatic arthritis.


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