The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 23, 2020

Filed:

Dec. 10, 2015
Applicants:

Yeda Research and Development Co. Ltd., Rehovot, IL;

University of Washington, Seattle, WA (US);

Inventors:

Dan S. Tawfik, Jerusalem, IL;

Haim Leader, Rehovot, IL;

Yaacov Ashani, Rehovot, IL;

Izhack Cherny, Rehovot, IL;

Moshe Goldsmith, Rehovot, IL;

Per Jr. Greisen, Seattle, WA (US);

Sagar D. Khare, Seattle, WA (US);

Gustav Oberdorfer, Seattle, WA (US);

David Baker, Seattle, WA (US);

Sarel Fleishman, Rehovot, IL;

Adi Goldenzweig, Rehovot, IL;

Nidhi Aggarwal, Rehovot, IL;

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/16 (2006.01); A61P 25/00 (2006.01); A62D 3/02 (2007.01); A62D 101/02 (2007.01); A62D 101/26 (2007.01);
U.S. Cl.
CPC ...
A62D 3/02 (2013.01); A61P 25/00 (2018.01); C12N 9/16 (2013.01); A62D 2101/02 (2013.01); A62D 2101/26 (2013.01); C12Y 301/08001 (2013.01);
Abstract

A genetically modified polypeptide is disclosed which comprises an amino acid sequence of phosphotriesterase (PTE) having at least twice the catalytic efficiency for a V-type nerve agent as a polypeptide which consists of the sequence as set forth in SEQ ID NO: 1, when assayed under identical conditions.


Find Patent Forward Citations

Loading…