The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 23, 2020

Filed:

Jun. 10, 2016
Applicant:

Teikyo University, Tokyo, JP;

Inventors:

Kazuo Maruyama, Tokyo, JP;

Ryo Suzuki, Tokyo, JP;

Johan Mikael Unga, Tokyo, JP;

Daiki Omata, Tokyo, JP;

Yusuke Oda, Tokyo, JP;

Assignee:

TEIKYO UNIVERSITY, Tokyo, JP;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 49/22 (2006.01); A61K 31/02 (2006.01); A61K 47/69 (2017.01); A61P 35/00 (2006.01); A61K 9/00 (2006.01); A61K 9/19 (2006.01); A61K 47/24 (2006.01); A61K 47/36 (2006.01); A61K 47/42 (2017.01);
U.S. Cl.
CPC ...
A61K 49/223 (2013.01); A61K 9/0009 (2013.01); A61K 9/19 (2013.01); A61K 31/02 (2013.01); A61K 47/24 (2013.01); A61K 47/36 (2013.01); A61K 47/42 (2013.01); A61K 47/6925 (2017.08); A61P 35/00 (2018.01);
Abstract

Provided is a theranostic bubble preparation which makes it possible to diagnose and treat a tissue of interest by the irradiation with ultrasound such as diagnostic ultrasound and low-intensity therapeutic ultrasound. The theranostic bubble preparation comprises: a coating film comprising a lipid; and a gas enclosed in an inner cavity formed in the coating film. The coating film comprises an anionic lipid made from distearoylphosphatidylcholine (DSPC), distearoylphosphatidylglycerol (DSPG) and 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] (DSPE-PEG). The gas and the mixed gas comprises perfluoropropane or perfluorobutane.


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