The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 23, 2020
Filed:
Jun. 18, 2019
Korea University Research and Business Foundation, Seoul, KR;
Jesang Ko, Seoul, KR;
Sodam Park, Jeonju-si, KR;
Abstract
The present invention relates to the 14-3-3 protein which is a non-alcoholic fatty liver regulating factor. According to the present invention, two isoform proteins of 14-3-3, i.e., 14-3-3β and 14-3-3γ, are different regulating factors for regulating the transcriptional activity of PPARγ. 14-3-3β increases the transcriptional activity of PPARγby binding to PPARγ, on the other hand, 14-3-3γ plays a role in decreasing the transcriptional activity of PPARγ. Thus, 14-3-3β and 14-3-3γ, which are PPARγregulating factors, are proteins that play a vital role in lipid metabolism, and may be used as a target for the prevention or treatment of fatty liver.