The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 23, 2020
Filed:
Apr. 23, 2019
Nangenex Nanotechnology Incorporated, Budapest, HU;
Erzsébet Réka Angi, Nagykovácsi, HU;
Tamás Jordán, Öcsöd, HU;
Richárd Balázs Kárpáti, Tatabánya, HU;
Gergo Patyi, Vecsés, HU;
Orsolya Basa-Dénes, Eger, HU;
Tamás Solymosi, Békéscsaba, HU;
Zsolt Ötvös, Csongrád, HU;
László Molnár, Biatorbágy, HU;
Hristos Glavinas, Szeged, HU;
Genovéva Filipcsei, Budapest, HU;
NanGenex Nanotechnology Incorporated, Budapest, HU;
Abstract
Disclosed herein are stable complexes with controlled particle size, increased apparent solubility and increased dissolution rate comprising as active compound Celecoxib, its salts, or derivatives thereof, which is useful in the treatment of osteoarthritis, rheumatoid arthritis, juvenile rheumatoid arthritis, ankylosing spondylitis, acute pain especially in cancer related acute pain, primary dysmenorrhea. More specifically, the complexes possess instantaneous redispersibility, increased apparent solubility and permeability that provide faster onset of action for acute pain relief and lower GI related side effects. Further disclosed are methods of formulating and manufacturing the complexes described herein, pharmaceutical compositions, and uses and methods of treatment.