The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 23, 2020

Filed:

Jun. 06, 2016
Applicant:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Inventors:

Junying Zheng, New Providence, NJ (US);

Walter Won, Alpine, NJ (US);

Michael Berlin, Flemington, NJ (US);

Pauline Ting, New Providence, NJ (US);

Guoqing Li, Belle Mead, NJ (US);

Dong Xiao, Somerset, NJ (US);

Hongwu Wang, Westfield, NJ (US);

Robert Aslanian, Rockaway, NJ (US);

Assignee:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/4162 (2006.01); A61K 31/519 (2006.01); A61K 31/497 (2006.01); A61P 25/00 (2006.01); A01N 43/80 (2006.01); C07D 487/04 (2006.01); C07D 487/10 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4162 (2013.01); A01N 43/80 (2013.01); A61K 31/497 (2013.01); A61K 31/519 (2013.01); A61P 25/00 (2018.01); C07D 487/04 (2013.01); C07D 487/10 (2013.01);
Abstract

Disclosed are compounds having the structure of Formula I, or a pharmaceutically acceptable salt of any thereof, wherein: 'Z', Rand Rare defined herein, which compounds are believed suitable for use in selectively antagonizing the A2a receptors, for example, those found in high density in the basal ganglia. Such compounds and pharmaceutical formulations are believed to be useful in treatment or management of neurodegenerative diseases, for example, Parkinson's disease, or movement disorders arising from use of certain medications used in the treatment or management of Parkinson's disease.


Find Patent Forward Citations

Loading…