The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 23, 2020

Filed:

Feb. 01, 2017
Applicant:

Clemson University, Clemson, SC (US);

Inventors:

Naren Vyavahare, Greenville, SC (US);

Aditi Sinha, Clemson, SC (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); A61K 9/51 (2006.01); A61K 39/44 (2006.01); C07K 16/18 (2006.01); C07K 16/28 (2006.01); A61K 47/69 (2017.01); A61K 47/68 (2017.01); A61K 47/02 (2006.01);
U.S. Cl.
CPC ...
A61K 9/5146 (2013.01); A61K 9/5153 (2013.01); A61K 39/44 (2013.01); A61K 47/02 (2013.01); A61K 47/6843 (2017.08); A61K 47/6937 (2017.08); C07K 16/18 (2013.01); C07K 16/2836 (2013.01);
Abstract

Methods and delivery agents for treatment of connective tissue that includes elastic fibers are described. Delivery agents are nano- or micro-sized particles that include a biologically active compound useful in treatment of degraded elastic fibers and an anchoring agent at a surface that binds at or near the area of degraded elastic fibers. The delivery agents may be utilized for targeted delivery of biologically active compounds to degraded elastic fibers so as to maintain and/or regenerate the elastin component of connective tissue, and prevent further degradation and/or rehabilitate the structural architecture of the connective tissue.


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