The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 23, 2020

Filed:

Nov. 21, 2017
Applicant:

Anp Technologies, Inc., Newark, DE (US);

Inventors:

Dujie Qin, Wilmington, DE (US);

Ray Yin, Wilmington, DE (US);

Jing Pan, Newark, DE (US);

Yubei Zhang, Hockessin, DE (US);

Assignee:

ANP Technologies, Inc., Newark, DE (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/14 (2006.01); A61K 47/58 (2017.01); A61K 31/4375 (2006.01); A61K 31/337 (2006.01); A61K 51/06 (2006.01); A61K 9/51 (2006.01); A61K 49/00 (2006.01); A61K 45/06 (2006.01); A61K 47/34 (2017.01); A61K 9/19 (2006.01); A61K 49/12 (2006.01); A61K 33/24 (2019.01); A61K 47/59 (2017.01); A61K 31/4745 (2006.01);
U.S. Cl.
CPC ...
A61K 9/14 (2013.01); A61K 9/19 (2013.01); A61K 9/513 (2013.01); A61K 9/5146 (2013.01); A61K 31/337 (2013.01); A61K 31/4375 (2013.01); A61K 31/4745 (2013.01); A61K 33/24 (2013.01); A61K 45/06 (2013.01); A61K 47/34 (2013.01); A61K 47/58 (2017.08); A61K 47/59 (2017.08); A61K 49/0004 (2013.01); A61K 49/12 (2013.01); A61K 51/06 (2013.01);
Abstract

Symmetrically and asymmetrically branched homopolymers are modified at the surface level with functional groups that enable forming aggregates with water insoluble or poorly water soluble pharmaceutically active agents (PAA). The aggregates formed are specifically induced by interaction of PAA and homopolymer and are different from aggregates that are formed by the polymer alone in the absence of the PAA or by the PAA alone in the absence of the polymer. Such aggregates can be used to improve drug solubility, stability, delivery and efficacy.


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