IDiyas

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10688047 B1

PDFFull Text
Date of Patent:
Jun. 23, 2020

Filed:

Oct. 28, 2016

Physically and chemically stable oral suspensions of givinostat

Applicant:

Italfarmaco Spa, Milan, IT;

Inventors:

Giuseppe Colombo, Seregno, IT;

Roberta Artico, Milan, IT;

Paolo Mascagni, Alicante, ES;

Maria Valmen Monzani, Milan, IT;

Silvia Puccianti, Corbetta, IT;

Assignee:

ITALFARMACO SPA, Milan, IT;

Attorney:

Hueschen and Sage

Primary Examiner:

Jennifer A Berrios

Int. Cl.
CPC ...
A61K 9/00 (2006.01); A61K 47/10 (2017.01); A61K 9/10 (2006.01); A61K 47/26 (2006.01); A61K 31/167 (2006.01); A61P 7/02 (2006.01); A61P 21/00 (2006.01); A61P 19/02 (2006.01); A61P 35/02 (2006.01); A61K 31/325 (2006.01); A61K 47/02 (2006.01); A61K 47/12 (2006.01); A61K 47/36 (2006.01);
U.S. Cl.
CPC ...
A61K 9/10 (2013.01); A61K 9/0053 (2013.01); A61K 9/0095 (2013.01); A61K 31/167 (2013.01); A61K 31/325 (2013.01); A61K 47/02 (2013.01); A61K 47/10 (2013.01); A61K 47/12 (2013.01); A61K 47/26 (2013.01); A61K 47/36 (2013.01); A61P 7/02 (2018.01); A61P 19/02 (2018.01); A61P 21/00 (2018.01); A61P 35/02 (2018.01);
Abstract

Physically and chemically stable oral liquid formulations of Givinostat (Diethyl-[6-(4-hydroxycarbamoyl-phenylcarbamoyloxymethyl)-naphthalen-2-yl-methyl]-ammonium chloride) are disclosed, together with methods for the preparation thereof. Such oral formulations are in the form of aqueous suspensions and contain Givinostat and/or pharmaceutically acceptable salts and/or derivatives thereof, at least a wetting agent and/or at least a density-imparting agent. Such formulations are suitable for oral administration for systemic therapeutic action.

Find Patent Forward Citations

Loading…