The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 16, 2020
Filed:
Jun. 13, 2018
Hoffmann-la Roche Inc., Nutley, NJ (US);
Christof Fattinger, Blauen, CH;
Hoffmann-La Roche Inc., Nutley, NJ (US);
Abstract
A method for the detection of binding affinities comprises providing a device having a planar waveguide () arranged on a substrate () and an optical coupler (). Coherent light () of a predetermined wavelength is coupled into the planar waveguide () such that the coherent light propagates along the planar waveguide (), with an evanescent field () of the coherent light propagating along an outer surface () of the planar waveguide (). Target samples () attached to binding sites () are arranged along a plurality of predetermined lines () on the outer surface () of the planar waveguide (). At a predetermined detection location, light of the evanescent field which is scattered by target samples () bound to binding sites () arranged along the predetermined lines () is detected. The light scattered by the target samples () bound to the binding sites () has, at the predetermined detection location, a difference in optical path length which is an integer multiple of the predetermined wavelength of the light.