The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 16, 2020

Filed:

Jun. 12, 2013
Applicant:

Nanyang Technological University, Singapore, SG;

Inventors:

Matthew Wook Chang, Singapore, SG;

Tat Ming Samuel Lo, Singapore, SG;

Chueh Loo Poh, Singapore, SG;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 15/74 (2006.01); C12P 7/62 (2006.01); C12N 9/00 (2006.01); C12N 15/67 (2006.01); C12N 9/88 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C12P 7/62 (2013.01); C12N 9/88 (2013.01); C12N 9/93 (2013.01); C12N 15/67 (2013.01); C12Y 402/01 (2013.01); C12Y 602/01012 (2013.01);
Abstract

An Expression system; isolated nucleic acid molecule or host cell comprising: (i) A first gene encoding for a first enzyme linked to a first promoter, wherein the first promoter is a time delay promoter; (ii) A second gene encoding for a second enzyme capable of using the product generated by the first enzyme as a substrate, wherein the second gene is operably linked to a second promoter, wherein the second promoter is inducible by the product generated by the first enzyme; (iii) Optionally, a third gene encoding a transcription factor that represses expression of the second gene in the absence of the product generated by the first enzyme, wherein the third gene is operably linked to a third promoter that regulates expression of the third gene; and its use in producing a product such as hydroxybenzaldehyde.


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