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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10683355 B1

PDFFull Text
Date of Patent:
Jun. 16, 2020

Filed:

Sep. 15, 2017

Genetically-modified cells and method for producing same

Applicants:

Kissei Pharmaceutical Co., Ltd., Matsumoto-shi, Nagano, JP;

Shinshu University, Matsumoto-shi, Nagano, JP;

Inventors:

Yozo Nakazawa, Matsumoto, JP;

Kazuyuki Matsuda, Matsumoto, JP;

Shigeru Nakano, Azumino, JP;

Assignees:

KISSEI PHARMACEUTICAL CO., LTD., Matsumoto-shi, Nagano, JP;

SHINSHU UNIVERSITY, Matsumoto-shi, Nagano, JP;

Attorney:

Westerman, Hattori, Daniels & Adrian, LLP

Primary Examiner:

Maria Marvich

Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 48/00 (2006.01); C07K 16/30 (2006.01); C07K 19/00 (2006.01); C12N 5/0783 (2010.01); C07K 16/28 (2006.01); A61K 31/7088 (2006.01); C12N 5/10 (2006.01); C07K 16/24 (2006.01); C07K 14/535 (2006.01); A61K 35/12 (2015.01); A61P 43/00 (2006.01); A61P 35/00 (2006.01); A61K 35/17 (2015.01); C07K 14/725 (2006.01); C07K 14/705 (2006.01); C12N 15/113 (2010.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2866 (2013.01); A61K 31/7088 (2013.01); A61K 35/12 (2013.01); A61K 35/17 (2013.01); A61K 39/001139 (2018.08); A61K 48/00 (2013.01); A61P 35/00 (2018.01); A61P 43/00 (2018.01); C07K 14/535 (2013.01); C07K 14/7051 (2013.01); C07K 14/70521 (2013.01); C07K 14/70578 (2013.01); C07K 16/243 (2013.01); C07K 19/00 (2013.01); C12N 5/0636 (2013.01); C12N 5/10 (2013.01); C12N 15/1136 (2013.01); A61K 38/00 (2013.01); A61K 2039/5156 (2013.01); A61K 2039/5158 (2013.01); A61K 2039/572 (2013.01); C07K 2317/524 (2013.01); C07K 2317/526 (2013.01); C07K 2317/53 (2013.01); C07K 2317/622 (2013.01); C07K 2317/76 (2013.01); C07K 2319/02 (2013.01); C07K 2319/03 (2013.01); C07K 2319/30 (2013.01); C12N 2310/122 (2013.01); C12N 2310/14 (2013.01); C12N 2310/531 (2013.01); C12N 2510/00 (2013.01);
Abstract

Production of a chimeric antigen receptor (CAR) expressing cell having excellent target cytotoxicity. Provided is a genetically modified cell comprising, introduced thereinto, a polynucleotide encoding a chimeric antigen receptor (CAR) protein having a target binding domain that specifically binds to a human granulocyte-macrophage colony stimulating factor (GM-CSF) receptor, a transmembrane domain and an intracellular signaling domain.

Find Patent Forward Citations

Nakazawa, Yozo. (2020). Genetically-modified cells and method for producing same (U.S. Patent No. 10683355). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10683355

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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