The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 16, 2020

Filed:

Apr. 20, 2018
Applicant:

Apogenix Ag, Heidelberg, DE;

Inventors:

Christian Gieffers, Dossenheim, DE;

Oliver Hill, Neckarsteinach, DE;

Meinolf Thiemann, Schriesheim, DE;

Tim Schnyder, Igersheim, DE;

Assignee:

Apogenix AG, Heidelberg, DE;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 14/52 (2006.01); C07K 16/46 (2006.01); C07H 21/04 (2006.01); C12N 15/63 (2006.01); C07K 14/705 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/70575 (2013.01); A61K 38/00 (2013.01); C07K 2319/00 (2013.01); C07K 2319/22 (2013.01); C07K 2319/30 (2013.01); C07K 2319/32 (2013.01); C07K 2319/35 (2013.01); C07K 2319/74 (2013.01);
Abstract

Provided herein are specific TL1A receptor agonist proteins, nucleic acids encoding the same, and methods of treating a subject having a TL1A-associated disease or disorder. The TL1A receptor agonist proteins provided herein comprise three soluble TL1A domains and an Fc fragment. The TL1A receptor agonist proteins are substantially non-aggregating and suitable for therapeutic, diagnostic and/or research applications.


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