The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 16, 2020
Filed:
Apr. 04, 2019
Applicant:
Roche Sequencing Solutions, Inc., Pleasanton, CA (US);
Inventors:
Michael Dorwart, Mountain View, CA (US);
Daniel Korenblum, San Francisco, CA (US);
Assignee:
Roche Sequencing Solutions, Inc., Pleasanton, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/31 (2006.01); C12Q 1/6869 (2018.01);
U.S. Cl.
CPC ...
C07K 14/31 (2013.01); C12Q 1/6869 (2013.01);
Abstract
Described herein are variants of alpha-hemolysin having at least one mutation selected from T12R, T12K, N17R, N17K or combinations of T12 and N17 mutations. The variants in some embodiments may further comprise H144A. The α-hemolysin variants have a decreased time to thread.