The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 16, 2020

Filed:

Nov. 10, 2018
Applicants:

Sunshine Lake Pharma Co., Ltd., Dongguan, Guangdong, CN;

Calitor Sciences, Llc, Newbury Park, CA (US);

Inventors:

Ning Xi, Newbury Park, CA (US);

Minxiong Li, Guangdong, CN;

Ju Peng, Guangdong, CN;

Xiaobo Li, Guangdong, CN;

Tao Zhang, Guangdong, CN;

Haiyang Hu, Guangdong, CN;

Wuhong Chen, Guangdong, CN;

Changlin Bai, Guangdong, CN;

Donghua Ke, Guangdong, CN;

Peng Chen, Guangdong, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/14 (2006.01); C07D 487/04 (2006.01); C07D 471/04 (2006.01); C07D 498/04 (2006.01); A61K 45/06 (2006.01); C07D 491/048 (2006.01); C07D 495/04 (2006.01); C07D 407/14 (2006.01); C07D 513/04 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); A61K 45/06 (2013.01); C07D 401/14 (2013.01); C07D 407/14 (2013.01); C07D 471/04 (2013.01); C07D 491/048 (2013.01); C07D 495/04 (2013.01); C07D 498/04 (2013.01); C07D 513/04 (2013.01);
Abstract

The present invention provides novel heteroaryl compounds, pharmaceutical acceptable salts and formulations thereof. They are useful in preventing, managing, treating or lessening the severity of a protein kinase-mediated disease. The invention also provides pharmaceutically acceptable compositions comprising such compounds and methods of using the compositions in the treatment of protein kinase-mediated disease.


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