The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 16, 2020
Filed:
Jul. 19, 2017
Nerviano Medical Sciences S.r.l., Nerviano (MI), IT;
Elena Casale, Somma Lombardo, IT;
Emiliana Corti, Nerviano, IT;
Paola Gnocchi, Stresa, IT;
Marcella Nesi, Saronno, IT;
Sten Christian Orrenius, Nerviano, IT;
Francesca Quartieri, Arona, IT;
Federico Riccardi Sirtori, Segrate, IT;
NERVIANO MEDICAL SCIENCES S.R.L., Nerviano (MI), IT;
Abstract
There are provided substituted purine and 3-deazapurine analogues, which modulate the activity of Choline Kinase (ChoK). The compounds of this invention are therefore useful in treating diseases caused by an altered choline metabolism, such as cancer, cell proliferative disorders, infectious diseases of different origin, immune-related disorders and neurodegenerative disorders. The present invention also provides methods for preparing these compounds, pharmaceutical compositions comprising these compounds, and methods of treating diseases utilizing pharmaceutical compositions comprising these compounds.