The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 16, 2020
Filed:
Aug. 07, 2018
Applicant:
Novartis Ag, Basel, CH;
Inventors:
Donatella Chianelli, San Diego, CA (US);
Xiaodong Liu, San Diego, CA (US);
Valentina Molteni, San Diego, CA (US);
John Nelson, San Diego, CA (US);
Jason Thomas Roland, San Diego, CA (US);
Paul Vincent Rucker, Carlsbad, CA (US);
David Charles Tully, Danville, CA (US);
Assignee:
Novartis AG, Basel, CH;
Primary Examiner:
Int. Cl.
CPC ...
C07D 231/54 (2006.01); A61K 31/4745 (2006.01); A61K 31/4439 (2006.01); A61K 31/4162 (2006.01); C07D 471/04 (2006.01); C07D 471/06 (2006.01); C07D 491/052 (2006.01); A61K 31/416 (2006.01);
U.S. Cl.
CPC ...
C07D 231/54 (2013.01); A61K 31/416 (2013.01); A61K 31/4162 (2013.01); A61K 31/4439 (2013.01); A61K 31/4745 (2013.01); C07D 471/04 (2013.01); C07D 471/06 (2013.01); C07D 491/052 (2013.01);
Abstract
The present invention relates to compounds of Formula I, a stereoisomer, enantiomer, a pharmaceutically acceptable salt or an amino acid conjugate thereof; wherein variables are as defined herein; and their pharmaceutical compositions, which are useful as modulators of the activity of Farnesoid X receptors (FXR).