The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 16, 2020

Filed:

Jun. 26, 2017
Applicant:

Bio-rad Laboratories, Inc., Hercules, CA (US);

Inventors:

Anthony J. Makarewicz, Jr., Livermore, CA (US);

Luc Bousse, Los Altos, CA (US);

Stefano Schiaffino, Pleasanton, CA (US);

Assignee:

Bio-Rad Laboratories, Inc., Hercules, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 1/00 (2006.01); B01L 3/00 (2006.01); B01L 7/00 (2006.01); C12N 15/10 (2006.01); C12Q 1/6806 (2018.01);
U.S. Cl.
CPC ...
B01L 3/502784 (2013.01); B01L 3/50273 (2013.01); B01L 3/502715 (2013.01); B01L 3/502746 (2013.01); B01L 7/52 (2013.01); C12N 15/1075 (2013.01); C12Q 1/6806 (2013.01); B01L 3/50853 (2013.01); B01L 2200/027 (2013.01); B01L 2300/04 (2013.01); B01L 2300/041 (2013.01); B01L 2300/044 (2013.01); B01L 2300/046 (2013.01); B01L 2300/0672 (2013.01); B01L 2300/0829 (2013.01); B01L 2300/0861 (2013.01); B01L 2300/0864 (2013.01); B01L 2400/049 (2013.01); B01L 2400/0457 (2013.01); B01L 2400/0487 (2013.01); B01L 2400/0655 (2013.01); B01L 2400/0677 (2013.01); B01L 2400/084 (2013.01); Y10T 436/2575 (2015.01);
Abstract

Microfluidic system, including methods and apparatus, for processing fluid, such as by droplet generation. In an exemplary method, a sample-containing fluid may be dispensed into a well through a sample port of a channel component. The channel component may include (a) a body having a bottom surface attached to the well, and a top surface with a microchannel formed therein, and (b) an input tube projecting into the well from the bottom surface of the body. The sample-containing fluid when dispensed may contact a bottom end of the input tube and may be retained, with assistance from gravity, out of contact with the microchannel. A pressure differential may be created that drives at least a portion of the sample-containing fluid from the well via the input tube and through the microchannel.


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