The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 16, 2020

Filed:

Apr. 08, 2016
Applicants:

Regencor, Inc., Los Altos, CA (US);

Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA (US);

Epikabio, Inc., Los Altos, CA (US);

Inventors:

Pilar Ruiz-Lozano, Los Altos, CA (US);

Mark Mercola, La Jolla, CA (US);

Ke Wei, Shanghai, CN;

Assignees:

Regencor, Inc., Los Altos, CA (US);

Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61K 38/16 (2006.01); C07K 1/00 (2006.01); A61K 47/42 (2017.01); A61K 35/34 (2015.01); A61K 9/00 (2006.01); A61K 9/70 (2006.01); A61K 38/17 (2006.01); A61K 31/7072 (2006.01); A61P 9/10 (2006.01); A61K 38/18 (2006.01);
U.S. Cl.
CPC ...
A61K 47/42 (2013.01); A61K 9/0024 (2013.01); A61K 9/7007 (2013.01); A61K 31/7072 (2013.01); A61K 35/34 (2013.01); A61K 38/1709 (2013.01); A61K 38/1875 (2013.01); A61P 9/10 (2018.01);
Abstract

Provided herein, inter alia, are compositions and kits comprising epicardial-derived paracrine factors (such as, hypoglycosylated follistatin-like 1 (FSTL1)) for treating and repairing damage to cardiac tissue caused by cardiovascular disease, myocardial infarction (MI), other ischemic events, or cardiac-growth deficiency, as well as methods for using the same.


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