The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 16, 2020

Filed:

Jun. 09, 2016
Applicants:

B. G. Negev Technologies and Applications Ltd, Beer Sheva, IL;

Children's Hospital Medical Center, Cincinnati, OH (US);

Inventors:

Joseph Kost, Omer, IL;

Tamar Traitel, Beer Sheva, IL;

Riki Goldbart, Lehavim, IL;

Shani Attias, Kiryat Motzkin, IL;

Paul Scot Kingma, Cincinnati, OH (US);

Jeffrey A. Whitsett, Cincinnati, OH (US);

Giora Enden, Tel-Aviv, IL;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/17 (2006.01); A61K 9/51 (2006.01); A61K 9/14 (2006.01); A61K 9/00 (2006.01); A61P 11/00 (2006.01);
U.S. Cl.
CPC ...
A61K 38/395 (2013.01); A61K 9/0073 (2013.01); A61K 9/146 (2013.01); A61K 9/5153 (2013.01); A61K 38/1709 (2013.01); A61P 11/00 (2018.01); A61K 9/0019 (2013.01); A61K 9/0043 (2013.01);
Abstract

A controlled release system includes surfactant protein D (SPD) and a carrier suitable for controlled release that can be polylactic-co-glycolic acid (PLGA). The system can be in the form of a nanoparticle. A pharmaceutical composition includes the system and a pharmaceutically acceptable carrier. Methods of treatment of a disease, disorder or condition associated with a decreased level of SPD in a subject, or for pulmonary delivery of SPD, include administering the pharmaceutical composition to a subject in need of such treatment.


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