The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 16, 2020
Filed:
May. 22, 2018
National Institute of Biological Sciences, Beijing, Beijing, CN;
Zhiyuan Zhang, Beijing, CN;
Xiaodong Wang, Beijing, CN;
Xiaoguang Lei, Beijing, CN;
Yaning Su, Beijing, CN;
Sudan He, Beijing, CN;
Hanying Ruan, Beijing, CN;
Liming Sun, Beijing, CN;
National Institute of Biological Sciences, Beijing, Beijing, CN;
Abstract
The invention provides amides that inhibit cellular necrosis and/or human receptor interacting protein 1 kinase (RIP1), including corresponding sulfonamides, and pharmaceutically acceptable salts, hydrates and stereoisomers thereof. The compounds are employed in pharmaceutical compositions, and methods of making and use, including treating a person in need thereof with an effective amount of the compound or composition, and detecting a resultant improvement in the person's health or condition.