The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 16, 2020

Filed:

Mar. 17, 2016
Applicant:

Regents of the University of Minnesota, Minneapolis, MN (US);

Inventors:

Ronald A. Siegel, Minneapolis, MN (US);

Mamta Kapoor, Minneapolis, MN (US);

Narsihmulu Cheryala, Minneapolis, MN (US);

Gunda I. Georg, Minneapolis, MN (US);

James C. Cloyd, Minneapolis, MN (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/48 (2006.01); A61K 9/00 (2006.01); A61K 31/5517 (2006.01); A61K 9/12 (2006.01); A61K 31/417 (2006.01); C07D 233/64 (2006.01);
U.S. Cl.
CPC ...
A61K 9/0043 (2013.01); A61K 9/12 (2013.01); A61K 31/417 (2013.01); A61K 31/5517 (2013.01); A61K 38/482 (2013.01); A61K 38/4813 (2013.01); C07D 233/64 (2013.01); C12Y 304/11006 (2013.01); C12Y 304/21063 (2013.01);
Abstract

Certain embodiments of the invention provide a formulation suitable for nasal administration comprising water, a prodrug of a therapeutic agent, and an enzyme that is suitable for intranasal conversion of the prodrug to the therapeutic agent, as well as methods of use thereof.


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