The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 09, 2020
Filed:
Feb. 20, 2018
Wisconsin Alumni Research Foundation, Madison, WI (US);
Wisconsin Alumni Research Foundation, Madison, WI (US);
Abstract
A system and method is provided to acquire images of a subject having received a tissue soluble hyperpolarized gas into the airways. The method includes performing a pulse sequence including (i) for each effective repetition time (TReff), acquiring at least one gas-phase dataset and at least one dissolved-phase dataset, wherein a gas-phase echo time (TEGas) of the at least one gas-phase dataset and a dissolved-phase echo time (TEDissolved) of the at least one dissolved-phase dataset are selected to isolate gas-phase contamination of the dissolved-phase dataset from dissolved-phase components in the dissolved-phase dataset. The method also includes (ii) estimating gas-phase contamination of the dissolved-phase dataset using the gas-phase dataset and a scaling factor (σ), (iii) producing a corrected dissolved-phase dataset by reducing the gas-phase contamination of the dissolved-phase dataset using the gas-phase contamination estimated in step (ii), and reconstructing an image from the corrected dissolved-phase dataset and the gas-phase dataset.