The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 09, 2020

Filed:

Jun. 14, 2019
Applicant:

National Chiao Tung University, Hsinchu, TW;

Inventors:

Jung-Chih Chen, Hsinchu, TW;

I-Chiu Li, Hsinchu, TW;

Kun-Che Li, Hsinchu, TW;

Ching-Cheng Chuang, Hsinchu, TW;

Mei-Lan Ko, Hsinchu, TW;

Han-Chien Chuang, Hsinchu, TW;

Ming-Hung Chien, Hsinchu, TW;

Yu-Rong Wang, Hsinchu, TW;

Hung-Ru Wang, Hsinchu, TW;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); G01N 33/68 (2006.01); G01N 21/78 (2006.01); G01N 33/58 (2006.01); G01N 27/02 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6896 (2013.01); G01N 21/78 (2013.01); G01N 33/587 (2013.01); G01N 27/026 (2013.01); G01N 2800/2821 (2013.01); G01N 2800/50 (2013.01);
Abstract

The invention relates to color-changing eye drops for early screening Alzheimer's disease and an application thereof. The color-changing eye drop for early screening Alzheimer's disease comprises 1 pg/ml to 10 ng/ml of Aβaptamer-gold nanoparticles (AuNPs) and a pharmaceutically acceptable carrier or vehicle thereof, which can be used to mix with a tear sample of a test subject to analyze a color change of the color-changing eye drop for determining the concentration proportion of Aβ:Aβcontained in the tear sample of the test subject.


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