The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 09, 2020

Filed:

Aug. 07, 2018
Applicant:

University Court of the University of St Andrews, St Andrews, GB;

Inventors:

Robert J H Hammond, Fife, GB;

Mario E. Giardini, Glasgow, GB;

Stephen H. Gillespie, Fife, GB;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 21/51 (2006.01); G01N 21/47 (2006.01); C12Q 1/18 (2006.01); C12Q 1/02 (2006.01); G01N 21/17 (2006.01); G01J 3/433 (2006.01); G01N 15/06 (2006.01); G01J 3/02 (2006.01); C12Q 1/00 (2006.01); G01N 21/03 (2006.01); G01N 21/53 (2006.01); G01N 15/02 (2006.01); C12Q 1/06 (2006.01); G01N 15/00 (2006.01); G01N 21/11 (2006.01); G01N 21/64 (2006.01);
U.S. Cl.
CPC ...
G01N 21/474 (2013.01); C12Q 1/00 (2013.01); C12Q 1/02 (2013.01); C12Q 1/06 (2013.01); C12Q 1/18 (2013.01); G01J 3/0254 (2013.01); G01J 3/433 (2013.01); G01N 15/0205 (2013.01); G01N 15/06 (2013.01); G01N 21/031 (2013.01); G01N 21/1717 (2013.01); G01N 21/51 (2013.01); G01N 21/53 (2013.01); G01J 2003/4334 (2013.01); G01N 21/11 (2013.01); G01N 2015/0065 (2013.01); G01N 2015/0222 (2013.01); G01N 2015/0693 (2013.01); G01N 2021/6469 (2013.01); G01N 2021/6482 (2013.01); G01N 2201/065 (2013.01); G01N 2201/0642 (2013.01); G01N 2201/06113 (2013.01);
Abstract

A system for measuring a liquid sample comprising biological material, the system comprising an integrating light collector for collecting light and for at least partially containing the sample; a light source for introducing light in the integrating light collector; a signal generator or modulator configured to cause a known modulation of the light output by the light source; a phase-sensitive detector for detecting scattered light in the integrating light collector; at least one of an exit port to allow un-scattered light to exit the integrating light collector, a beam dump, or a baffle arranged to absorb unscattered light; and a processor configured to analyse the detected modulated light to determine changes in the detected modulated light as a function of time thereby to determine at least one of: drug susceptibility of the biological material; a change in a number of cells in the sample; a change in cell state; a change in the biological material.


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