The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 09, 2020

Filed:

Nov. 30, 2018
Applicants:

Life Technologies Corporation, Carlsbad, CA (US);

Life Technologies As, Carlsbad, CA (US);

Inventors:

Geir Fonnum, Oslo, NO;

Steven M. Menchen, Fremont, CA (US);

Alfred Lui, Sunnyvale, CA (US);

Guobing Xiang, Hayward, CA (US);

Synne Larsen, Oslo, NO;

Assignees:

LIFE TECHNOLOGIES CORPORATION, Carlsbad, CA (US);

LIFE TECHNOLOGIES AS, Oslo, NO;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2018.01); C12Q 1/6876 (2018.01); C12Q 1/6874 (2018.01); C12Q 1/6869 (2018.01); C08J 7/14 (2006.01); C12Q 1/6853 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/6874 (2013.01); C08J 7/14 (2013.01); C12Q 1/6853 (2013.01); C12Q 1/6869 (2013.01); C12Q 1/6876 (2013.01); C08J 2333/26 (2013.01);
Abstract

A polymer substrate, such as a polymer coating or a polymer hydrogel network, includes carboxyl moieties that can be used as conjugation sites to which receptor or analyte molecules can be attached. In an example, the polymer substrate includes a polyacrylamide polymer network having alkanoic acid moieties or derivatives thereof, which can react with carboxyl activating compounds to provide an activated alkanoate moieties on the polyacrylamide network. Amine-terminated nucleic acids can react with the activated alkanoate moieties to capture the nucleic acid to the polymer network through an alkylamide moiety.


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