The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 09, 2020

Filed:

Jun. 13, 2013
Applicant:

Eberhard Karls Universitaet Tuebingen, Tuebingen, DE;

Inventors:

Anna Kristina Jehle, Tuebingen, DE;

Martin Lipschis, Bremen, DE;

Markus Albert, Tuebingen, DE;

Georg Felix, Tuebingen, DE;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/82 (2006.01); C07K 14/415 (2006.01); C12N 15/62 (2006.01); C07K 14/195 (2006.01);
U.S. Cl.
CPC ...
C12N 15/8281 (2013.01); C07K 14/195 (2013.01); C07K 14/415 (2013.01); C12N 15/62 (2013.01);
Abstract

The present invention relates to the finding that an until now orphan protein named receptor-like protein 1 (RLP1) in plants mediates an immune response to bacterial infections. Specifically, the invention relates to RLP1, now named receptor of enigmatic microbe-associated molecular pattern (MAMP) of(REMAX), inREMAX was found to recognise the presence ofand to initiate an immune signalling that eventually yields into a typical plant immune responses to bacterial infections. Furthermore, the invention relates to chimeric pattern recognition receptors (PRRs) composed of the extracellular domain of REMAX, which is the recognition site for sensing infection, and c-terminal portions of PRRs of other plant species. Also provided is a method to modulate the immune response of a plant to a bacterial infection by either increasing or decreasing the expression of REMAX or REMAX-like proteins, or the inventive chimeric PRRs in plants. Finally, the invention provides methods for the identification and purification of new microbe-associated molecular patterns in plants using REMAX or REMAX-like proteins and/or the novel chimeric PRRs of the present invention.


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