The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 09, 2020

Filed:

May. 23, 2017
Applicant:

Corning Incorporated, Corning, NY (US);

Inventors:

Huayun Deng, Painted Post, NY (US);

Ye Fang, Painted Post, NY (US);

Qiang Fu, Painted Post, NY (US);

Aize Li, Painted Post, NY (US);

Lina Ma, Corning, NY (US);

John Christopher Mauro, Corning, NY (US);

Assignee:

Corning Incorporated, Corning, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/00 (2006.01); C03C 3/145 (2006.01); C03C 4/00 (2006.01); C03C 3/16 (2006.01); C03C 3/21 (2006.01); C03C 3/062 (2006.01); C03C 3/17 (2006.01); C03C 3/064 (2006.01); C03C 3/19 (2006.01); C12N 5/071 (2010.01);
U.S. Cl.
CPC ...
C12N 5/0068 (2013.01); C03C 3/062 (2013.01); C03C 3/064 (2013.01); C03C 3/145 (2013.01); C03C 3/16 (2013.01); C03C 3/17 (2013.01); C03C 3/19 (2013.01); C03C 3/21 (2013.01); C03C 4/0007 (2013.01); C03C 4/0014 (2013.01); C03C 4/0035 (2013.01); C12N 5/069 (2013.01); C12N 2500/30 (2013.01); C12N 2501/105 (2013.01); C12N 2501/11 (2013.01); C12N 2501/115 (2013.01); C12N 2501/165 (2013.01); C12N 2501/30 (2013.01); C12N 2501/91 (2013.01); C12N 2533/12 (2013.01);
Abstract

A borophosphate glass composition including BO, PO, and CaO, and optionally a source additive selected from: LiO, NaO, KO, AlO, ZnO, MgO, FeO/FeO, CuO/CuO, and mixtures thereof, as defined herein. Also disclosed are bioactive compositions or substrates including the disclosed borophosphate glass composition, and at least one live cell. Also disclosed are methods of inhibiting or increasing the relative amount of species containing boron, phosphorous, or both, being released into an aqueous solution from aborophosphate glass composition defined herein. Also disclosed is a method of proliferating cells on a bioactive substrate as defined herein. Also disclosed are related glass compositions that exclude one of BO, PO, and CaO.


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