The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 09, 2020

Filed:

Jul. 31, 2015
Applicant:

Oncotherapy Science, Inc., Kawasaki-shi, JP;

Inventors:

Takuya Tsunoda, Kawasaki, JP;

Ryuji Osawa, Kawasaki, JP;

Sachiko Yamashita, Kawasaki, JP;

Tomohisa Watanabe, Kawasaki, JP;

Assignee:

ONCOTHERAPY SCIENCE, INC., Kawasaki-shi, JP;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 14/47 (2006.01); A61K 38/04 (2006.01); A61K 38/08 (2019.01); A61K 39/395 (2006.01); G01N 33/50 (2006.01); A61K 35/12 (2015.01); C07K 7/06 (2006.01); C12N 15/09 (2006.01); C07K 7/08 (2006.01); C07K 16/28 (2006.01); A61K 48/00 (2006.01); A61K 38/00 (2006.01); C12N 5/10 (2006.01); A61K 35/14 (2015.01); A61K 39/00 (2006.01); C07K 16/18 (2006.01); G01N 33/574 (2006.01);
U.S. Cl.
CPC ...
C07K 14/4738 (2013.01); A61K 35/12 (2013.01); A61K 35/14 (2013.01); A61K 38/00 (2013.01); A61K 38/04 (2013.01); A61K 38/08 (2013.01); A61K 39/0011 (2013.01); A61K 39/395 (2013.01); A61K 48/00 (2013.01); C07K 7/06 (2013.01); C07K 7/08 (2013.01); C07K 16/18 (2013.01); C07K 16/28 (2013.01); C12N 5/10 (2013.01); C12N 15/09 (2013.01); G01N 33/505 (2013.01); G01N 33/574 (2013.01); A61K 2039/5154 (2013.01); A61K 2039/572 (2013.01); G01N 2333/47 (2013.01);
Abstract

The present invention provides CDCA1-derived epitope peptides having the ability to induce cytotoxic T cells. The present invention further provides polynucleotides encoding the peptides, antigen-presenting cells presenting the peptides, and cytotoxic T cells targeting the peptides, as well as methods of inducing the antigen-presenting cells or CTLs. The present invention also provides compositions and pharmaceutical compositions containing them as an active ingredient. Further, the present invention provides methods of treating and/or preventing cancer, and/or preventing postoperative recurrence thereof, using the peptides, polynucleotides, antigen-presenting cells, cytotoxic T cells or pharmaceutical compositions of the present invention. Methods of inducing an immune response against cancer are also provided.


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