The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 09, 2020

Filed:

Mar. 03, 2016
Applicants:

Colorado State University Research Foundation, Fort Collins, CO (US);

Dana-farber Cancer Institute, Inc., Boston, MA (US);

University of Notre Dame Du Lac, South Bend, IN (US);

Inventors:

Robert M. Williams, Fort Collins, CO (US);

James E. Bradner, Weston, MA (US);

Dane Clausen, Rahway, NJ (US);

Olaf G. Wiest, South Bend, IN (US);

Tenaya L. Newkirk, Denver, CO (US);

Albert A. Bowers, Chapel Hill, NC (US);

Jennifer Marie Guerra, Henderson, NV (US);

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); C07K 5/062 (2006.01); C07D 513/18 (2006.01); A61K 31/429 (2006.01); A61K 31/437 (2006.01); A61K 45/06 (2006.01); A61K 38/05 (2006.01); C07B 59/00 (2006.01);
U.S. Cl.
CPC ...
C07K 5/06052 (2013.01); A61K 31/429 (2013.01); A61K 31/437 (2013.01); A61K 38/05 (2013.01); A61K 45/06 (2013.01); C07B 59/008 (2013.01); C07D 513/18 (2013.01); C07B 2200/05 (2013.01);
Abstract

Analogs of largazole are described herein. Methods of treating cancer and blood disorders using largazole and largazole analogs and pharmaceutical compositions comprising the same are additionally described herein. Methods for preparing largazole analogs are likewise described.


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