The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 09, 2020
Filed:
Jun. 02, 2016
Applicant:
Teva Pharmaceuticals International Gmbh, Jona, CH;
Inventors:
Vinod Kumar Kansal, Haryana, IN;
Dhirenkumar Natvarial Mistry, Gujarat, IN;
Srinivas Achanta, Uttarpradesh, IN;
Sundaraselvan Ariyamuthu, Tamilnadu, IN;
Miteshgir Kanchangir Goswami, Gujarat, IN;
Venkata Subbarao Yazali, Pradesh, IN;
Assignee:
Teva Pharmaceuticals International GmbH, Jona, CH;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 43/04 (2006.01); A61K 31/70 (2006.01); C07H 19/20 (2006.01); C07H 19/10 (2006.01); C07F 9/24 (2006.01); C07H 1/00 (2006.01); C07F 9/6558 (2006.01); C07H 1/04 (2006.01); A61K 31/635 (2006.01); A61K 9/00 (2006.01); A61K 45/06 (2006.01); A61K 31/7072 (2006.01); A61K 31/505 (2006.01); A61P 31/04 (2006.01); A61K 31/708 (2006.01); C07B 57/00 (2006.01); C07B 63/02 (2006.01);
U.S. Cl.
CPC ...
C07H 19/20 (2013.01); C07F 9/2458 (2013.01); C07F 9/65583 (2013.01); C07H 1/00 (2013.01); C07H 1/04 (2013.01); C07H 19/10 (2013.01); A61K 9/0053 (2013.01); A61K 31/505 (2013.01); A61K 31/635 (2013.01); A61K 31/708 (2013.01); A61K 31/7072 (2013.01); A61K 45/06 (2013.01); A61P 31/04 (2018.01); C07B 57/00 (2013.01); C07B 63/02 (2013.01); C07B 2200/07 (2013.01);
Abstract
The present disclosure provides procedures and intermediates for the preparation of Sofosbuvir, comprising the step of reacting a compound of formula 2: wherein Rand Rcan independently be hydrogen or halogen, provided that at least one of Rand Ris a halogen.