The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 09, 2020

Filed:

Sep. 23, 2016
Applicants:

Université DE Bretagne Occidentale, Brest, FR;

Inserm (Institut National DE LA Santé ET DE LA Recherche Médicale, Paris, FR;

Centre Hospitalier Régional ET Universitaire DE Brest, Brest, FR;

Inventors:

Paul-Alain Jaffrès, Bohars, FR;

Hélène Couthon-Courvès, Bohars, FR;

Damien Afonso, Brest, FR;

Tristan Montier, Brest, FR;

Tony Le Gall, Brest, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 217/28 (2006.01); C07F 9/24 (2006.01); A61K 9/127 (2006.01); C12N 15/88 (2006.01);
U.S. Cl.
CPC ...
C07F 9/2458 (2013.01); A61K 9/127 (2013.01); C07C 217/28 (2013.01); C12N 15/88 (2013.01);
Abstract

Disclosed are novel branched amphiphilic lipids, in particular novel branched amphiphilic lipids of general formula (II). Also disclosed is a method of synthesis for the compounds of formula (II), from unsaturated amphiphilic compounds of general formula (I). Further disclosed is the use of the compounds of general formula (II) and of the lipoplexes obtained by formulation of the compounds of general formula (II) for applications, particularly transfection, in which improved fusion properties are desired.


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