The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 09, 2020
Filed:
Dec. 15, 2017
Applicants:
Cstone Pharmaceuticals, Grand Cayman, KY;
Medshine Discovery Inc., Nanjing, Jiangsu, CN;
Inventors:
Zhaobing Xu, Shanghai, CN;
Lihong Hu, Shanghai, CN;
Charles Z. Ding, Shanghai, CN;
Shuhui Chen, Shanghai, CN;
Assignees:
CSTONE PHARMACEUTICALS, Grand Cayman, KY;
MEDSHINE DISCOVERY INC., Nanjing, Jiangsu, CN;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/497 (2006.01); C07D 241/20 (2006.01); C07D 471/04 (2006.01); A61P 35/00 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); A61P 35/00 (2018.01); C07D 519/00 (2013.01);
Abstract
Disclosed is a series of compounds acting as CDK4/6 inhibitors. Specifically disclosed are compounds as represented by formula (I), pharmaceutically acceptable salts or isomers thereof, pharmaceutical compositions containing same, and the use thereof in the preparation of drugs for treating cancers.