The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 09, 2020
Filed:
Jul. 02, 2018
Applicants:
Zhude Tu, Frontenac, MO (US);
Adam Rosenberg, Nashville, MO (US);
Hui Liu, Creve Coeur, MO (US);
Junbin Han, Shanghai, CN;
Inventors:
Zhude Tu, Frontenac, MO (US);
Adam Rosenberg, Nashville, MO (US);
Hui Liu, Creve Coeur, MO (US);
Junbin Han, Shanghai, CN;
Assignee:
Washington University, St. Louis, MO (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 413/04 (2006.01); C07D 419/04 (2006.01); C07D 413/10 (2006.01); C07D 271/06 (2006.01); C07B 59/00 (2006.01); C07D 413/12 (2006.01);
U.S. Cl.
CPC ...
C07D 413/04 (2013.01); C07B 59/002 (2013.01); C07D 271/06 (2013.01); C07D 413/10 (2013.01); C07D 413/12 (2013.01); C07B 2200/05 (2013.01);
Abstract
Among the various aspects of the present disclosure is the provision of a compositions for binding sphingosine-1-phosphate receptor 1 (S1P1), imaging of S1P1, and methods of use thereof. Provided are imaging agents for imaging S1P1 and S1P1 associated diseases, disorders, and conditions. Also provided are therapeutic compositions and methods for the treatment of S1P1 associated diseases, disorders, and conditions.