The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 09, 2020

Filed:

Mar. 24, 2017
Applicant:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Inventors:

Michael Miller, Scotch Plains, NJ (US);

Harry R. Chobanian, Aberdeen, NJ (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 215/14 (2006.01); C07D 401/04 (2006.01); C07D 201/00 (2006.01); A61K 31/47 (2006.01); A61K 31/4709 (2006.01); A61K 31/4725 (2006.01); A61K 31/538 (2006.01); A61K 45/06 (2006.01); C07D 265/36 (2006.01); C07D 413/04 (2006.01);
U.S. Cl.
CPC ...
C07D 401/04 (2013.01); A61K 31/47 (2013.01); A61K 31/4709 (2013.01); A61K 31/4725 (2013.01); A61K 31/538 (2013.01); A61K 45/06 (2013.01); C07D 201/00 (2013.01); C07D 215/14 (2013.01); C07D 265/36 (2013.01); C07D 413/04 (2013.01);
Abstract

Novel compounds of the structural formula (I), and the pharmaceutically acceptable salts thereof, are agonists of G-protein coupled receptor 40 (GPR40) and may be useful in the treatment, prevention and suppression of diseases mediated by the G-protein-coupled receptor 40. The compounds of the present invention may be useful in the treatment of Type 2 diabetes mellitus, and of conditions that are often associated with this disease, including obesity and lipid disorders, such as mixed or diabetic dyslipidemia, hyperlipidemia, hypercholesterolemia, and hypertriglyceridemia.


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