The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 09, 2020
Filed:
Apr. 25, 2019
Applicant:
PH Pharma Co., Ltd., Seoul, KR;
Inventors:
Heiko Schirmer, Solingen, DE;
Philipp Rubenbauer, Dusseldorf, DE;
Birgit Keil, Dusseldorf, DE;
Britta Olenik, Bottrop, DE;
Assignee:
pH Pharma Co., Ltd., Seoul, KR;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 239/22 (2006.01); C07C 315/00 (2006.01);
U.S. Cl.
CPC ...
C07D 239/22 (2013.01); C07C 315/00 (2013.01); C07B 2200/13 (2013.01);
Abstract
The invention relates to a new and improved method for preparation of (4S)-4-[4-cyano-2-(methyl sulfonyl)phenyl]-3,6-dimethyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-1,2,3,4-tetrahydro pyrimidine-5-carbonitrile of formula (I), as well as the preparation and use of the crystal form (A) of (4S)-4-[4-cyano-2-(methylsulfonyl)phenyl]-3,6-dimethyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-1,2,3,4-tetrahydro pyrimidine-5-carbonitrile of formula (I).