The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 09, 2020
Filed:
Sep. 11, 2015
Applicant:
Kyoto Prefectural Public University Corporation, Kyoto, JP;
Inventors:
Assignee:
KYOTO PREFECTURAL PUBLIC UNIVERSITY CORPORATION, Kyoto, JP;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61L 27/38 (2006.01); C12N 5/079 (2010.01); A61K 35/30 (2015.01); A61L 27/00 (2006.01); A61K 35/12 (2015.01); C12N 15/09 (2006.01); C12N 5/10 (2006.01); A61P 25/00 (2006.01); A61L 27/36 (2006.01); A61L 27/54 (2006.01);
U.S. Cl.
CPC ...
A61L 27/383 (2013.01); A61K 35/12 (2013.01); A61K 35/30 (2013.01); A61L 27/00 (2013.01); A61L 27/3675 (2013.01); A61L 27/3895 (2013.01); A61L 27/54 (2013.01); A61P 25/00 (2018.01); C12N 5/0622 (2013.01); C12N 5/10 (2013.01); C12N 15/09 (2013.01); A61L 2430/32 (2013.01); C12N 2501/60 (2013.01); C12N 2506/09 (2013.01); C12N 2506/1384 (2013.01); C12N 2506/28 (2013.01);
Abstract
The present invention addresses the problem of providing a method for obtaining Schwann cells directly (by direct reprogramming) without passing through pluripotent stem cells, such as ES cells or iPS cells. As a means for solving this problem, the present invention provides a method for preparing Schwann cells that includes a step of introducing into somatic cells of a mammal at least one gene selected from the group consisting of SOX10 genes and KROX20 genes, or an expression product thereof.