The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 09, 2020
Filed:
Sep. 29, 2016
Korea Atomic Energy Research Institute, Daejeon, KR;
Yong-Dae Park, Jeollabuk-do, KR;
Jung-Joon Min, Gwangju, KR;
Seung-Dae Yang, Jeollabuk-do, KR;
Min-Goo Hur, Gyeonggi-do, KR;
Seung-Jin Jung, Jeollanam-do, KR;
Yeong-Jin Hong, Gwangju, KR;
Seung-Hwan Park, Gwangju, KR;
Korea Atomic Energy Research Institute, Daejeon, KR;
Abstract
The present invention relates to a curcumin derivative, a method for producing same, and a photo-acoustic imaging agent comprising the curcumin derivative for detecting beta-amyloid plaque. The curcumin derivative, expressed by chemical formula 1, according to the present invention exhibits superb selective bonding with beta-amyloid, thereby allowing beta-amyloid to be detected by means of an optical or photo-acoustic imaging methods, and, particularly, the curcumin derivative can highly effectively detect photo-acoustic signals with almost no noise by reacting to irradiation of light having a particular wavelength range, and thus can be useful as a composition for detecting beta-amyloid and for diagnosing diseases caused by excessive production of beta-amyloid.