The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 09, 2020

Filed:

Nov. 05, 2019
Applicant:

Amgen Inc., Thousand Oaks, CA (US);

Inventors:

Gary Luehr, Hayward, CA (US);

Shabbir T. Anik, San Francisco, CA (US);

Ge Peng, Mountain View, CA (US);

Irina Dotsenko, San Jose, CA (US);

Pasit Phiasivongsa, Brentwood, CA (US);

Dante Romanini, Sherman Oaks, CA (US);

Assignee:

AMGEN INC., Thousand Oaks, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 405/12 (2006.01); A61K 38/07 (2006.01); A61K 47/60 (2017.01); A61K 9/00 (2006.01); C08G 65/333 (2006.01);
U.S. Cl.
CPC ...
A61K 47/60 (2017.08); A61K 9/0019 (2013.01); A61K 9/0053 (2013.01); A61K 38/07 (2013.01); C07D 405/12 (2013.01); C08G 65/33396 (2013.01); C08G 2230/00 (2013.01);
Abstract

The present invention provides a method of treating multiple myeloma using polymeric pegylated carfilzomib compounds, and pharmaceutically acceptable salts thereof, of Formula I wherein R, R, linker, PEG, n and o are as defined herein.


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