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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10675328 B1

PDFFull Text
Date of Patent:
Jun. 09, 2020

Filed:

Feb. 14, 2018

Compositions and methods for treatment of gcase related disease states

Applicant:

Children's Hospital Medical Center, Cincinnati, OH (US);

Inventor:

Ying Sun, Mason, OH (US);

Assignee:

Children's Hospital Medical Center, Cincinnati, OH (US);

Attorney:

Frost Brown Todd, LLC

Primary Examiner:

Kimberly Ballard

Assistant Examiner:

Stacey N MacFarlane

Int. Cl.
CPC ...
A61K 38/17 (2006.01); A61P 25/28 (2006.01); A61K 45/06 (2006.01); A61K 38/47 (2006.01); A61K 48/00 (2006.01); C12N 7/00 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
A61K 38/1777 (2013.01); A61K 9/0019 (2013.01); A61K 38/47 (2013.01); A61K 45/06 (2013.01); A61K 48/005 (2013.01); A61P 25/28 (2018.01); C12N 7/00 (2013.01); C12Y 302/01045 (2013.01); A01K 2227/105 (2013.01); A01K 2267/0362 (2013.01); A61K 48/00 (2013.01); C12N 2740/15041 (2013.01); C12N 2740/16043 (2013.01);
Abstract

Disclosed are compositions and methods of treating a neurodegenerative disease in an individual. The methods disclose administration of an Integrin α4β1, Very Late Antigen-4 positive neural precursor cell ('VLA4+ NPC') transfected with a lentivirus overexpressing wild type GCase to an individual having a neurodegenerative disorder. The neurodegenerative disease may include lipid storage diseases, for example Gaucher disease, Parkinson's disease (PD), Dementia with Lewy bodies.

Find Patent Forward Citations

Sun, Ying. (2020). Compositions and methods for treatment of gcase related disease states (U.S. Patent No. 10675328). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10675328

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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